LocalFree

UniProt MCP server

smaniches/uniprot-mcp

Query the UniProt knowledgebase (entries, features, variants, PTMs, GO terms, cross-references) with per-query SHA-256 provenance and offline replay.

3 GitHub stars
Source code

Install UniProt in Claude Code

Claude Code
claude mcp add uniprot -- uvx uniprot-mcp-server
mcp.json (Claude Desktop, Cursor, VS Code, Windsurf)
{
  "mcpServers": {
    "uniprot": {
      "command": "uvx",
      "args": [
        "uniprot-mcp-server"
      ]
    }
  }
}

Frequently asked questions

What does the UniProt MCP server do?

Query the UniProt knowledgebase (entries, features, variants, PTMs, GO terms, cross-references) with per-query SHA-256 provenance and offline replay.

Is the UniProt MCP server free?

Yes, most likely. Open source and no paid account or API key is mentioned in the listing. Check the provider for current pricing.

Does UniProt run locally or remotely?

Local. Runs on your machine (stdio). You install it with npx, uvx, Docker or from source.

How do I add UniProt to Claude Code?

Run: claude mcp add uniprot -- uvx uniprot-mcp-server

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