Reactome MCP Server: Install & Setup

Install Reactome in Claude Code

Remote URL

Claude Code

claude mcp add --transport http reactome https://gateway.pipeworx.io/reactome/mcp

mcp.json (Claude Desktop, Cursor, VS Code, Windsurf)

{
  "mcpServers": {
    "reactome": {
      "url": "https://gateway.pipeworx.io/reactome/mcp"
    }
  }
}

npm

Claude Code

claude mcp add reactome -- npx -y @pipeworx/mcp-reactome

mcp.json (Claude Desktop, Cursor, VS Code, Windsurf)

{
  "mcpServers": {
    "reactome": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-reactome"
      ]
    }
  }
}

Frequently asked questions

What does the Reactome MCP server do?

Reactome MCP — open biological pathway knowledge-base.

Is the Reactome MCP server free?

Yes, most likely. Open source and no paid account or API key is mentioned in the listing. Check the provider for current pricing.

Does Reactome run locally or remotely?

Local + Remote. Can run locally or be used as a hosted remote server.

How do I add Reactome to Claude Code?

Run: claude mcp add --transport http reactome https://gateway.pipeworx.io/reactome/mcp

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