Pubchem MCP Server: Install & Setup

Install Pubchem in Claude Code

Remote URL

Claude Code

claude mcp add --transport http pipeworx-io-pubchem https://gateway.pipeworx.io/pubchem/mcp

mcp.json (Claude Desktop, Cursor, VS Code, Windsurf)

{
  "mcpServers": {
    "pipeworx-io-pubchem": {
      "url": "https://gateway.pipeworx.io/pubchem/mcp"
    }
  }
}

npm

Claude Code

claude mcp add pipeworx-io-pubchem -- npx -y @pipeworx/mcp-pubchem

mcp.json (Claude Desktop, Cursor, VS Code, Windsurf)

{
  "mcpServers": {
    "pipeworx-io-pubchem": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-pubchem"
      ]
    }
  }
}

Frequently asked questions

What does the Pubchem MCP server do?

PubChem MCP — NIH chemistry compound database (no auth)

Is the Pubchem MCP server free?

Yes, most likely. Open source and no paid account or API key is mentioned in the listing. Check the provider for current pricing.

Does Pubchem run locally or remotely?

Local + Remote. Can run locally or be used as a hosted remote server.

How do I add Pubchem to Claude Code?

Run: claude mcp add --transport http pipeworx-io-pubchem https://gateway.pipeworx.io/pubchem/mcp

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