Uniprot MCP Server: Install & Setup

Install Uniprot in Claude Code

Remote URL

Claude Code

claude mcp add --transport http cyanheads-uniprot https://uniprot.caseyjhand.com/mcp

mcp.json (Claude Desktop, Cursor, VS Code, Windsurf)

{
  "mcpServers": {
    "cyanheads-uniprot": {
      "url": "https://uniprot.caseyjhand.com/mcp"
    }
  }
}

npm

Claude Code

claude mcp add cyanheads-uniprot -- npx -y @cyanheads/uniprot-mcp-server

mcp.json (Claude Desktop, Cursor, VS Code, Windsurf)

{
  "mcpServers": {
    "cyanheads-uniprot": {
      "command": "npx",
      "args": [
        "-y",
        "@cyanheads/uniprot-mcp-server"
      ]
    }
  }
}

Frequently asked questions

What does the Uniprot MCP server do?

Protein research over UniProtKB: search by function, fetch curated records, map IDs, proteomes.

Is the Uniprot MCP server free?

Yes, most likely. Open source and no paid account or API key is mentioned in the listing. Check the provider for current pricing.

Does Uniprot run locally or remotely?

Local + Remote. Can run locally or be used as a hosted remote server.

How do I add Uniprot to Claude Code?

Run: claude mcp add --transport http cyanheads-uniprot https://uniprot.caseyjhand.com/mcp

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